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Test ID: SGUR Specific Gravity, Random, Urine


Ordering Guidance


Urine with contrast dye, glucose, or excessive protein should not be evaluated with this test. In these cases, urine osmolality is a better measure of urine concentration. Order UOSMU / Osmolality, Random, Urine.



Specimen Required


Container/Tube: Plastic urine container

Specimen Volume: 20 mL

Collection Instructions:

1. Collect a random urine specimen.

2. No preservative.


Useful For

As a partial assessment of the kidney's ability to concentrate urine

Method Name

Refractometer

Reporting Name

Specific Gravity, U

Specimen Type

Urine

Specimen Minimum Volume

1 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Urine Refrigerated (preferred) 7 days
  Frozen  7 days

Clinical Information

Specific gravity (SG), the ratio of the mass of a solution compared to the mass of an equal volume of water, is an estimate of the concentration of substances dissolved in the solution.

 

Urine SG can be used to assess the kidney's ability to concentrate or dilute urine. However, because protein, glucose, and contrast dye have molecular masses that are relatively large compared to other major components of urine (eg, sodium, chloride, potassium), they disproportionately affect SG. In these cases, urine osmolality is a better measure of urine concentration

Reference Values

1.002-1.030

Interpretation

Low specific gravity (SG) (1.001-1.003) may indicate the presence of diabetes insipidus, a disease caused by impaired functioning of antidiuretic hormone (ADH). Low SG also can occur in patients with glomerulonephritis, pyelonephritis, and other renal abnormalities. In these cases, the kidney has lost its ability to concentrate due to tubular damage.

 

High SG may occur in patients with adrenal insufficiency, hepatic disease, congestive heart failure, or in patients experiencing excessive water loss due to sweating, fever, vomiting, or diarrhea.

Clinical Reference

1. Schumann GB, Schweitzer SC: Examination of urine. In: Kaplan LA, Pesce AJ, eds. Clinical Chemistry, Theory, Analysis and Correlation. 3rd ed. Mosby-Year Book Inc; 1996:1118-1119

2. Free HM, ed: Modern Urine Chemistry (Manual). 8th ed. Bayer Corp; 1996:36-37

3. Perrier ET, Bottin JH, Vecchio M, Lemetais G: Criterion values for urine-specific gravity and urine color representing adequate water intake in healthy adults. Eur J Clin Nutr. 2017 Feb;71:561-563

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

LOINC Code Information

Test ID Test Order Name Order LOINC Value
SGUR Specific Gravity, U 5810-7

 

Result ID Test Result Name Result LOINC Value
SGUR Specific Gravity, U In Process

Forms

If not ordering electronically, complete, print, and send a Renal Diagnostics Test Request (T830) with the specimen.

Day(s) Performed

Monday through Sunday

Report Available

Same day/1 day
Mayo Clinic Laboratories | Renal Diagnostics Catalog Additional Information:

mcl-kidney